Prions are a unique group of proteinaceous pathogens which cause neurodegenerative disease and can be transmitted by a variety of exposure routes.After peripheral exposure, the accumulation and replication of prions within secondary lymphoid organs are obligatory for their efficient spread from the periphery to the brain where they ultimately cause
Medicinal plants have been used since ancient times, acquiring broad interest in their healing properties due to their active compounds.The Peruvian Amazon rainforest has a great variety of flora, such as monocots (Dracontium loretense Krause and Commelina diffusa) and dicotyledons (Dysphania ambrosioides, Malva sylvestris, Origanum vulgare, Bixa o
While percutaneous closure of patent foramen ovale (PFO) and atrial septal defect (ASD) are generally well-tolerated procedures, the development of postprocedure fever has been observed at a higher frequency than reported in the initial device trials.We performed a retrospective analysis of 62 patients who underwent PFO or ASD closure from January
Dendritic cells (DC) are a diverse group of leukocytes responsible for bridging innate and adaptive immunity.Despite their functional versatility, DCs exist primarily in two basic functional states: immature Baby Shorts and mature.A large body of evidence suggests that upon interactions with pathogens, DCs undergo intricate cellular processes that